PHYTOCHEMICAL AND ANTI BACTERIAL ACTIVITY OF ZIZIPHUS MUCRANATA LEAVES EXTRACT

Garba U.,  Gayari, M.S., Boyi, M.Y and  S/Dogarai, B.B

Department of Chemistry

Shehu Shagari College of Education Sokoto

Email: umar.g4000@gmail.com

ABSTRACT

This research work investigate on the major active chemical constituents present in the leave of the ziziphus mucranata (Ramnaceae) and anti-bacterial activity of different extracts of the plant leaves. Ziziphus mucronata (Rhamnaceae), commonly known as buffalo thorn, is native to Northern Nigeria. The percentage yield (%) of the extracts were quantified, whereby Aq, MeOH, Ethyl acetate and DCM extracts possessed 0.92%, 2.20%, 1.98% and 1.65% respectively. Conclusively, Leaves of Ziziphus mucronata reveal some degree of anti-bacterial activities against staphylococcus and E.coli, these activities may be traced to either alkaloids or steroids. These indicate that most of medicinal plants used in ethnomedicine are potentially useful pharmacological and nutraceutical in the treatment of some pathogenic microorganisms. This research may contribute to the clear understanding of antibacterial activities of the plant. Health benefits and biodiesel/biofuel of the plant should be tested.

Keywords: Phytochemical, Antibacterial, Extraction, Ramnacea, ethnomedicine, biofuel.