Comparative Study on the Haematological Characteristics of Malaria Infected and Malaria Non-Infected Persons Referred to Art/HIV Laboratory, Abia State University
Teaching Hospital, Aba, Abia State.
1Etusim, P.E., 2Ihemanma, C.A., 1Nduka, F.O., 3Melariri P.E., and 4Ukpai, O.
1Unit of Medical Parasitology and Entomology, Faculty of Biological and Physical Sciences,
Abia State University, Uturu.
2Unit of Medical Microbiology and Parasitology, Abia State Polytechnic, Aba.
3Division of Pharmacology, Department of Medicine, University of Cape Town Medical School K45, Old
Main Building Groote Schuur Hospital, Observatory 7925, South Africa.
4Department of Zoology, Michael Okpara University of Agriculture, Umudike, Abia State.
Email addresses: etusimp@gmail.com, adaokey1981@yahoo.com
ABSTRACT
People infected with HIV/AIDS frequently have hematological derangements which include anaemia, Leucopenia, and Thrombocytopenia. In this study, hematological
parameters between malaria positive(+) and negative(–) HIV infected persons referred to ART/HIV laboratory, Abia State University teaching hospital, Aba were compared.
Blood samples collected for haematological assays were run using an automated full blood counter and malaria parasitaemia was determined by blood smear microscopy. A
total of 490 adults living with HIV parasites were examined. Of these 373(76.1%) were found to have malaria while 117(23.3%) had no malaria infection. Haematological analysis of blood samples showed higher mean values of RBC (×1012 /μL)(4.66±4.28 for
(–)/3.80±2.30, for (+),WBC(×109/μL)(5.39±1.68 for (–)/5.35±3.61 for (+), HB(g/dl)(12.16±2.41 for (–)/10.44±2.09 for (+),HCT(%)(36.42±6.71 for (–)/32.45±15.82
for (+),MCH(pg)(28.67±3.76 for (–/28.32±4.38 for (+), MCHC(g/dl)(33.28±1.38 for (–)/32.64±2.37 for (+), PLT(x109/μL)(233.56±123.26 for (–)/227.20±93.98 for (+)LYM(%)(50.83±56.78 for (–)/41.53±13.67 for (+), NEUT(%)(39.68±14.66 for (–
)/37.98±19.19 for (+), for malaria uninfected persons. Lower mean values of MCV (FL)(85.54±10.03 for (–)/86.63±11.09 for (+), MXD(%)(16.08±9.93 for (–)/23.04±28.83
for (+) were observed in malaria uninfected persons. The variation seen in the mean