Induction of Microcytic-Hypochromic Anaemia in Clarias gariepinus (Burchell, 1822) Exposed to Sublethal Toxicity of 2, 3-Dichlorovinyl Dimethyl Phosphate (Sniper 1000EC) Under Laboratory Conditions

Abubakar, M.I¹ and Abdulsalami, S.A². 

¹Department of Biology, School of Sciences, College of Education, Zuba, Abuja, Nigeria. 

²Department of Biological Sciences, Crescent University, Sapon Abeokuta, Ogun State, Nigeria.

Email: a.midiog@yahoo.com

ABSTRACT

Microcytic-hypochromic anaemia was induced in Clarias gariepinus (Burchell, 1822) at intervals of 1, 14 and 28 days.  Experimental fish were exposed to test water separately diluted with sub lethal concentrations of sniper 1000EC of 0, 0.27, 0.31, 0.41 and 0.55mg/L. A 28 days exposure to sublethal concentrations of the toxicant resulted in changes in heamatological parameters of the fish on the exposure days (1, 14 and 28). Blood dyscrasias attributable to microcytic- hypochromic anaemia  was observed with a significant (p<0.05) decrease in haemoglobin, haematocrit, red blood cells, white blood cells, lymphocytes, monocytes, mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH) and mean corpuscular haemoglobin concentration (MCHC). Neutrophils, eosinophil and basophil increased significantly (p<0.05) with increasing concentrations of the toxicant.